Regen3 Complex pairs a biomimetic exosome serum with SkinPen microneedling to support firmer, smoother, better-quality skin. Delivered as a four-session course at L’Atelier Aesthetics on Harley Street, with consultation and clinical oversight by Dr Brennand and minimal downtime.
Regen3 Complex by Nouveau Visage is a regenerative treatment that combines SkinPen microneedling with a biomimetic exosome serum to improve skin quality, texture and firmness with minimal downtime. It is delivered as a course of four sessions over about two months at L’Atelier Aesthetics on Harley Street, with the consultation and clinical oversight provided by Dr Brennand and the treatment carried out by Kate or Bronte.
Regen3 Complex pairs a biomimetic exosome serum with SkinPen microneedling to support firmer, smoother, better-quality skin, delivered as a short course at our Harley Street clinic with minimal downtime.
At L’Atelier Aesthetics, Regen3 Complex is one of the regenerative treatments patients ask about when they want to improve skin quality without injections. People often search for “exosome microneedling London”, “exosome facial near me” or “microneedling with serum cost” when they are ready to address texture, dullness and early laxity, and this is exactly where medical expertise matters. Regen3 Complex combines SkinPen microneedling with a biomimetic exosome serum, so the two work together to stimulate collagen and elastin. Our approach is consultation-led, personalised and always focused on natural, healthy results.
Anaesthetic | Numbing cream |
Treatment time | 45 to 60 minutes, including numbing |
Downtime | Mild redness for 24 to 48 hours |
Results | Skin feels smoother within days; collagen-led results build from four to six weeks |
Number of sessions | Four-session course, two weeks apart (around two months in total) |
Duration of results | Builds over the course and maintained between sessions with the take-home serum |
Delivered by | Kate or Bronte, with consultation and clinical oversight by Dr Brennand |
Priced from | £2,200 per course of 4x £550 sessions (including serum) |
Regen3 Complex is a course of SkinPen microneedling carried out with a biomimetic exosome serum from Nouveau Visage that combines exosomes, polynucleotides and peptides. The microneedling creates fine channels in the surface of the skin while the serum is applied on top, so the two work together to support collagen and elastin and improve overall skin quality.
Regen3 Complex is a topical treatment used during microneedling. Nothing is injected. The exosomes are biomimetic, which means they are made in a laboratory to mimic the signalling vesicles your own cells use, rather than being taken from human or animal tissue.
Microneedling uses very fine needles to create controlled micro-channels in the outer layer of skin. This prompts a mild, controlled repair response, which is the mechanism behind standard microneedling. Regen3 Complex builds on that by applying a regenerative serum to the skin at the same time.
The serum carries exosomes alongside polynucleotides and peptides, two ingredient groups widely used in skin regeneration to support hydration, repair and collagen production. Because the serum is applied to freshly microneedled skin, more of it can reach beyond the surface than it would from a cream alone. The aim is to give the skin clearer instructions to rebuild collagen and elastin, while calming the treated area so recovery tends to be quicker and more comfortable than microneedling on its own.
Regen3 Complex is aimed at skin quality rather than volume. It is well suited to fine lines, dull or tired-looking skin, uneven texture and tone, visible pores and the early signs of skin laxity. It is used mainly on the face, and the course includes the neck so the two areas are treated together for a more even result.
Regen3 Complex uses the Newderm biomimetic exosome serums by Nouveau Visage. Each is built around the same exosome, polynucleotide and peptide base, with the formula tuned to a particular concern:
Dr Brennand will recommend which serum, or combination of serums, suits your skin at the consultation.
Regen3 Complex tends to suit you well if any of the following apply:
It may not be the right first choice in the following situations:
“Regen3 Complex suits patients who want to improve skin quality and texture without injections or significant downtime. We deliver it as a course of four sessions two weeks apart, and most patients see smoother, brighter skin from around four to six weeks as new collagen develops. If the main concern is volume loss or pronounced laxity, I usually recommend an injectable or energy-based option instead at the consultation.”
Dr Duncan Brennand, Lead Aesthetic Doctor, GMC reference 4341662.
Regen3 Complex combines biomimetic exosome serums with SkinPen microneedling to improve skin quality with minimal downtime, delivered as a four-session course at L’Atelier Aesthetics on Harley Street. The best next step is to book a consultation with Emma, Bronte or Kate to confirm whether it suits your skin and which Regen3 Newderm serum to use.
Regen3 Complex is a course of SkinPen microneedling carried out with a biomimetic exosome serum from Nouveau Visage that combines exosomes, polynucleotides and peptides. The microneedling creates fine channels in the surface of the skin while the serum is applied on top, so the two work together to stimulate collagen and elastin and improve overall skin quality.
No. With Regen3 Complex the serum is applied to the skin during microneedling rather than injected, and the exosomes are biomimetic, meaning they are made in a laboratory rather than taken from human or animal tissue. It is a topical treatment used alongside microneedling, not an injectable.
The standard course is four sessions spaced two weeks apart, so the treatment runs over about two months. Dr Brennand confirms the right number for your skin at the consultation.
Most patients find Regen3 Complex comfortable. A numbing cream is applied before the microneedling, and because nothing is injected the sensation is limited to the microneedling itself, which feels like light pressure and vibration.
Downtime is usually mild. Expect 24 to 48 hours of redness similar to light sunburn, which the exosome serum tends to help settle more quickly than microneedling on its own.
Skin often feels smoother and looks brighter within a few days of the first session. The collagen-led improvement in firmness and texture builds gradually from around four to six weeks and continues over the course of the treatment.
We welcome patients from across Marylebone, Mayfair, Fitzrovia, Regent’s Park, Soho, Knightsbridge, Belgravia, Chelsea and Kensington, as well as visitors travelling to London for specialist aesthetic and skin treatments. Our location benefits from excellent transport links, with Oxford Circus only a 13 minute walk away, Bond Street and Regent’s Park Underground stations are also both within easy reach. The clinic is also conveniently accessible from major London rail stations and Heathrow, Gatwick and London City airports thanks to the Elizabeth line, making visits straightforward for both UK and international patients.
Whether you are travelling from within London or further afield, our Harley Street clinic provides a calm, professional environment for personalised aesthetic and skin health treatments in one of the capital’s most respected medical locations.
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