Deeply hydrate and remodel your skin from within with Profhilo, a bio-remodelling skin booster available at our Harley Street clinic.
Profhilo is an injectable treatment made from a high concentration of pure hyaluronic acid. Unlike traditional dermal fillers, it is not designed to add volume or change facial contours. Instead, it spreads beneath the skin to deliver deep hydration, while stimulating the skin’s own collagen and elastin production.
This bio-remodelling action helps to improve skin laxity, tone and overall quality, making Profhilo a popular choice for patients who want healthier, more radiant skin with a natural-looking result.
Profhilo can be used on the face, neck, décolletage and hands, and is suitable for most adults looking to refresh and rejuvenate the quality of their skin.
During treatment, a series of small injections are placed at specific points across the treated area. Once beneath the skin, the hyaluronic acid spreads slowly through the tissue, drawing in moisture and hydrating the skin from within.
This process also stimulates four different types of collagen and elastin, supporting the skin’s own structure over time. Because the effect builds gradually, results tend to look subtle and natural rather than sudden or overdone.
Most patients are recommended a course of two treatments around four weeks apart, allowing the skin time to respond fully between sessions.
Your Profhilo journey begins with a consultation, where your practitioner will assess your skin, discuss your goals and confirm whether Profhilo, Profhilo Structura or a combination approach is most suitable.
On the day of treatment, the skin is cleansed and, if needed, a topical numbing cream is applied. A series of small injections are then placed at specific points across the treated area, with the full session typically taking 30 to 45 minutes.
Following treatment, aftercare guidance is provided to support your results. A follow-up session is usually recommended around four weeks later to complete your course and assess your progress.
There are several hyaluronic acid based skin boosters available, each with a slightly different formulation and approach. The table below offers a general comparison to help you understand the differences, though the most suitable treatment for you will always be confirmed at consultation.
| Treatment | Formulation | General focus |
|---|---|---|
Profhilo | High concentration, low molecular weight hyaluronic acid | Hydration, elasticity and overall skin remodelling |
Seventy Hyal | Hyaluronic acid based skin booster | Hydration and skin quality, with a different concentration profile to Profhilo |
Sunekos | Hyaluronic acid combined with amino acids | Supports the skin's own production of collagen and elastin |
Polynucleotides | DNA-derived polynucleotides | Skin repair, regeneration and tissue quality |
Profhilo may be suitable for patients who are noticing early signs of skin laxity, dehydration or a loss of radiance. It is often considered by patients who wish to:
Suitability will always be confirmed during a consultation, where your practitioner will assess your skin and discuss the most appropriate treatment plan for your goals.
Profhilo is commonly used to improve skin quality in areas affected by dehydration and mild laxity.
A typical Profhilo treatment session takes around 30 to 45 minutes, depending on the areas being treated.
As with any injectable treatment, individual results vary from patient to patient, and your practitioner will discuss realistic expectations with you during consultation.
| Area | Description |
|---|---|
Face | Improves overall hydration, tone and radiance across the full face. |
Décolletage | Improves skin quality and texture across the chest area |
Neck | Supports skin firmness and helps reduce the appearance of crepiness. |
Hands | Helps restore hydration and a smoother appearance to the backs of the hands. |
Profhilo and dermal fillers are both hyaluronic acid based treatments, but they work in different ways and are designed for different goals.
Traditional dermal fillers are typically placed in specific areas to add volume, for example along the cheeks, lips or jawline. Profhilo, on the other hand, is not designed to add volume or reshape facial contours. Instead, it spreads across the treated area to hydrate the skin and stimulate collagen and elastin, improving skin quality rather than structure.
Because of this, Profhilo is often described as a skin booster rather than a filler. It is frequently used alongside dermal fillers as part of a broader treatment plan, addressing skin quality and structural concerns together.
The most suitable option, or combination of options, will depend on your individual skin and goals, which your practitioner will discuss with you during consultation.
Most patients can return to their normal routine immediately after Profhilo, with only minimal downtime.
Immediately after treatment, you may notice:
Aftercare guidance:
If you experience persistent swelling, signs of infection or any unexpected changes in the treated area, please contact our Harley Street clinic promptly.
If you still have questions, or would like to speak to a member of the team. You can contact us by; Phone, Email, WhatsApp and WebForm. It is our upmost priority that during your stay at 101 Harley Street, whether in our surgical or non surgical clinic, you feel safe, relaxed, and comfortable, so please do not hesitate to reach out to any of our highly trained team should you require anything.
Profhilo is often grouped with dermal fillers because it is hyaluronic acid based, but it works differently. Rather than adding volume, it spreads through the skin to deliver hydration and stimulate collagen and elastin, which is why it is generally described as a skin booster rather than a filler.
Dermal fillers are typically used to add volume to specific areas, such as the cheeks or lips. Profhilo instead spreads across the treated area to improve skin quality, hydration and elasticity without changing facial structure.
Profhilo Structura is designed to restore structural support in the superficial fat layer of the face, helping with contour and lift. Standard Profhilo focuses on hydration and overall skin quality. Many patients benefit from a combination of both.
Results generally last around six to nine months, depending on individual factors such as skin quality and lifestyle. Maintenance treatments are often recommended to help sustain results.
Many patients find Profhilo a worthwhile treatment for improving skin hydration, tone and overall quality with minimal downtime. Whether it is the right treatment for you will depend on your individual skin concerns and goals, which can be discussed during a consultation.
Profhilo is a well-studied treatment that works by stimulating the skin’s own collagen and elastin production while delivering deep hydration. Most patients notice an improvement in skin quality and radiance following a course of treatment.
As with any injectable treatment, there is a small risk of side effects such as bruising, swelling or lumps at injection sites, which usually resolve on their own. Choosing an experienced, appropriately qualified practitioner significantly reduces these risks, and any concerns following treatment should always be raised with your clinic promptly.
Both are hyaluronic acid based skin boosters, but Sunekos combines hyaluronic acid with amino acids, while Profhilo uses a high concentration, low molecular weight hyaluronic acid formulation. Your practitioner can advise which is best suited to your skin during consultation.
Polynucleotide treatments focus on skin repair and regeneration using DNA-derived ingredients, while Profhilo focuses on hydration and stimulating collagen and elastin. Some patients benefit from combining both as part of a wider skin health plan.
Profhilo is not injected directly beneath the eyes, but treating the surrounding mid and lower face can achieve a subtle lifting and hydrating effect that improves the overall appearance of the eye area.
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We welcome patients from across Marylebone, Mayfair, Fitzrovia, Regent’s Park, Soho, Knightsbridge, Belgravia, Chelsea and Kensington, as well as visitors travelling to London for specialist aesthetic and skin treatments. Our location benefits from excellent transport links, with Oxford Circus only a 13 minute walk away, Bond Street and Regent’s Park Underground stations are also both within easy reach. The clinic is also conveniently accessible from major London rail stations and Heathrow, Gatwick and London City airports thanks to the Elizabeth line, making visits straightforward for both UK and international patients.
Whether you are travelling from within London or further afield, our Harley Street clinic provides a calm, professional environment for personalised aesthetic and skin health treatments in one of the capital’s most respected medical locations.
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