
Dermamelan treatment at our Harley Street skin clinic is used to remove and improve all forms of pigmentation, like melasma and dark spots.
The Dermamelan® Pigmentation Programme is a deep chemical peel designed t o specifically target stubborn pigmentation, uneven skin tone, and discoloration at its source. Penetrating beyond the surface, it works to regulate melanin production, effectively fading dark spots, melasma, and sun damage.
By promoting deep exfoliation and skin renewal, this intensive treatment delivers transformative, long-lasting results revealing a brighter, clearer, and more even complexion. Includes aftercare pack.
Hyperpigmentation occurs when too much melanin is produced in a localised area resulting in dark spots and irregular skin colouration. There are several potential factors which cause hyperpigmentation including sun exposure, ageing, hormonal changes, medication and genetic tendencies.
The Dermamelan pigmentation treatment consists of an in-clinic treatment mask followed by a long-term home care programme that effectively act on all phases of the hyperpigmentation process. By using an advanced and exclusive combination of 6 laboratory-formulated ingredients, we can help eliminate existing hyperpigmentation, prevent its reappearance and stop the formation of new dark spots.* This is achieved through an intensive corrective effect that regulates the overproduction of melanin to keep hyperpigmentation under control.


This treatment is designed to target pigmentation, melasma, sun damage, sun spots, post inflammatory hyperpigmentation, and uneven skin tone. The Dermamelan Programme corrects existing pigmentation while preventing new pigmentation from forming, helping to restore a brighter, more even complexion.
This medical grade treatment combines an in clinic procedure with a carefully structured home care phase over four months. The process works by inhibiting the enzyme tyrosinase to regulate melanin production and renew the skin at a cellular level. It is suitable for all skin types and tones, including those affected by hormonal or sun induced pigmentation.
Patients can expect visible improvement within two to four weeks, with continued enhancement throughout the treatment programme.
Treatment preparation time: 2 weeks
Treatment duration: 4 months
Sensation: +++++
Peeling: Skin flaking for up to 1 month
Included: Pre peel skin preparation, in clinic Dermamelan mask, post peel products, follow up consultations, and Visia skin scans






If you still have questions, or would like to speak to a member of the team. You can contact us by; Phone, Email, WhatsApp and WebForm. It is our upmost priority that during your stay at 101 Harley Street, whether in our surgical or non surgical clinic, you feel safe, relaxed, and comfortable, so please do not hesitate to reach out to any of our highly trained team should you require anything.
After a period of 30 to 60 days, hyperpigmentation caused by the overproduction of melasma should fade and disappear. If you follow the homecare programme as advised, results should be long term.*
It’s important to avoid certain treatments during the therapy, such as peels and facials.
There may be some peeling, redness and irritation after the in-clinic treatment. This may last until the application (homecare programme) is reduced in the 2nd month.*
No, it may also be used on the body. It’s ideal for areas where hyperpigmentation often occurs such as hands, arms, décolletage and the back and shoulders.
We’ll recommend a number of products from Mesoestetic – a world-leading pharmaceutical laboratory specialising in dermatology and cosmetic medicine. These will include a hydra-milk cleanser, hydratonic, fast skin repair, hydra-vital factor k and moisturising sun protection SPF 50+. The products are to be used alongside the homecare programme and are available as a post-peel pack. Using the products will help to reduce irritation, peeling and chances of adverse reactions.
Products containing Vitamin C or retinols should be avoided throughout the treatment as they will over stimulate the skin.
Skin is particularly sensitised during the first month after the in-clinic treatment. That’s why we recommend using only the products contained in the post-peel pack with the maintenance cream.
After the first month when irritation reduces, we may recommend introducing products from the Mesoestetic W+ whitening range.
*Individual results may vary.
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Considering a Dermamelan treatment? Learn more through our blog articles.