By the team at L’Atelier Aesthetics, checked by Dr Duncan Brennand, Lead Aesthetic Doctor, 101 Harley Street
Skin boosters have become one of the most consistently requested treatment categories in aesthetic medicine, and the number of products on the market has grown considerably. Profhilo, Sunekos and Seventy Hyal are three of the most frequently asked-about options at L’Atelier Aesthetics on Harley Street.
They are not interchangeable. Each works differently, suits different presenting concerns, and produces a different quality of result. This guide sets out how they compare in clinical practice, and which one is recommended most often at the clinic.
For most patients with a loss of skin quality, mild laxity and early signs of ageing, Profhilo is the first recommendation. It contains the highest concentration of non-crosslinked hyaluronic acid available in a licensed aesthetic product, produces a well-documented collagen response, and carries the most robust clinical evidence base of the three.
Sunekos is a genuinely different product with a different purpose. The addition of amino acids makes it particularly suited to thinner, more crepey skin around the eyes, where rebuilding the dermal matrix is the primary goal. Seventy Hyal is a lower-cost option that can work well in younger skin, but for an ageing face the evidence does not match Profhilo’s clinical performance.
Skin boosters are injected into the dermis rather than into deeper tissue planes. They are not volumisers and they do not alter the shape of the face. The active ingredient in all three products is hyaluronic acid, which hydrates the skin immediately on injection by attracting and holding water in the tissue. Over the following weeks, it also signals the skin to produce new collagen and elastin – which is where the gradual firming and improvement in skin quality comes from.
The differences between products come down to the concentration of hyaluronic acid, how it has been formulated, how it spreads through the dermis, and whether any additional ingredients are included. Concentration drives the collagen response. Additional ingredients – such as the amino acids in Sunekos – target specific concerns in specific skin types.
Skin boosters are well suited to patients from their mid-thirties onwards who have noticed their skin looking duller, thinner or more crepey than it previously did. Common presentations include early softening along the jawline, dull or dehydrated cheeks, crepey texture on the neck or decolletage, and general loss of skin vitality without significant volume loss.
Skin boosters are not the right treatment where:
The primary concern is volume loss in a specific area – this requires a dermal filler conversation
There is significant laxity along the jawline or neck – a booster alone will not lift the tissue, and an energy-based tightening treatment may need to be incorporated into the plan
Dr Brennand will confirm at consultation whether a skin booster is the appropriate recommendation, and which product is best suited to the presenting concern.
Profhilo leads on evidence and collagen stimulation. For an ageing face with a general loss of skin quality, it consistently produces the most visible improvement. Sunekos has a specific and genuinely useful role in the periorbital area and in very thin, fragile skin where the amino acid component supports dermal matrix repair. Seventy Hyal is an appropriate option in younger patients with early skin quality concerns, but it is not the product of first choice for patients over forty at this clinic.
Patients sometimes ask about polynucleotides as a fourth option. Polynucleotides sit in a different clinical category – they are primarily a repair-focused treatment rather than a hydration booster – and are particularly useful where the skin has been damaged or where the periorbital area is the primary concern.
| Variable | Profhilo | Sunekos | Seventy Hyal |
|---|---|---|---|
HA concentration | 64 mg/2 ml (highest) | Medium, plus amino acids | 70 mg/2 ml (varied) |
Biostimulation | Strong, 4 collagen types | Moderate, matrix support | Mild to moderate |
Best for | Face, neck, jawline, hands | Under-eye, thin skin | Younger skin, face |
Course | 2 sessions, 4 weeks apart | 4 sessions, 1 week apart | 2 sessions, 4 weeks apart |
L’Atelier Aesthetics is a doctor-led clinic at 101 Harley Street, London. Every skin booster treatment begins with a clinical consultation with Dr Duncan Brennand, who assesses the skin and selects the most appropriate product before any treatment is planned.
Dr Brennand is a GMC-registered aesthetic doctor with over a decade of experience on Harley Street. His GMC reference number is 4341662, verifiable on the GMC medical register.
The clinic is at 101 Harley Street, London W1G 6AH, a short walk from Bond Street, Oxford Circus and Regent’s Park underground stations.
“If a patient presents asking for a skin booster and they have an ageing face, the recommendation will be Profhilo. The evidence is stronger, the effect on jawline skin is visibly better, and a two-session course is more realistic for most patients than returning for four Sunekos visits. Sunekos has a specific and appropriate role in thin periorbital skin, and I do reach for it there. Seventy Hyal works in younger skin, but I would not choose it over Profhilo in a patient over forty.”
Dr Duncan Brennand, Lead Aesthetic Doctor, L’Atelier Aesthetics
At L’Atelier Aesthetics, all skin booster injections are delivered personally by Dr Brennand. The product selection is made at consultation based on skin quality, age, the presenting concern and any previous treatments the patient has had.
At L’Atelier Aesthetics, Profhilo is the skin booster we recommend first for most patients with an ageing face, because of its higher hyaluronic acid concentration and stronger evidence for collagen stimulation. Sunekos is the better choice for thin periorbital skin, where amino acids help rebuild the dermal matrix. Dr Brennand decides between them at consultation based on the skin in front of him.
A Profhilo course at L’Atelier Aesthetics is two sessions spaced four weeks apart. Sunekos is four sessions spaced one week apart. Seventy Hyal is usually two sessions spaced four weeks apart. Maintenance, once the initial course is complete, is typically a single session every six months.
Skin boosters are placed with very fine needles and most patients describe them as a brief stinging sensation that settles within seconds. We use a topical anaesthetic for patients who prefer it. There is no significant downtime; small injection bumps can remain for an hour or two afterwards.
Profhilo downtime at L’Atelier Aesthetics is minimal. Expect small raised injection points for up to 24 hours, which settle on their own. Mild bruising can appear at an injection site and clears within a few days. Makeup can be applied the next morning.
Yes. Skin boosters and dermal fillers work in different planes and are routinely combined. Profhilo sits in the dermis to improve skin quality, while filler sits deeper to restore volume. Dr Brennand will plan the sequence and timing at consultation so the two treatments do not interfere with each other.
We welcome patients from across Marylebone, Mayfair, Fitzrovia, Regent’s Park, Soho, Knightsbridge, Belgravia, Chelsea and Kensington, as well as visitors travelling to London for specialist aesthetic and skin treatments. Our location benefits from excellent transport links, with Oxford Circus only a 13 minute walk away, Bond Street and Regent’s Park Underground stations are also both within easy reach. The clinic is also conveniently accessible from major London rail stations and Heathrow, Gatwick and London City airports thanks to the Elizabeth line, making visits straightforward for both UK and international patients.
Whether you are travelling from within London or further afield, our Harley Street clinic provides a calm, professional environment for personalised aesthetic and skin health treatments in one of the capital’s most respected medical locations.
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