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Profhilo vs Dermal Fillers: Hydration, Structure or Both?

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Profhilo vs Dermal Fillers: Hydration, Structure or Both?

Injectable skin treatments are often grouped together as if they all do the same thing.

But not all injectables are designed to add volume or change the shape of your face. Some are there to restore structure. Others focus on improving skin quality.

Understanding the difference is key when comparing Profhilo vs dermal fillers – because they’re not competing treatments. In many cases, they do completely different jobs.

If you’re trying to decide between skin hydration vs volume, here’s what each option actually does, and how to choose what’s right for you.

Why the terminology causes so much confusion

Many patients come to the L’Atelier clinic in Harley Street asking for a specific product they’ve seen online, without being entirely sure what it actually does. Terms like “dermal filler”, “skin booster” and “hydration treatment” are often used interchangeably, which can make very different injectable skin treatments sound the same.

In reality, they work in different ways and at different layers of the face. Some improve skin quality and hydration, while others restore structure and volume. Understanding that distinction makes choosing the right treatment much simpler – and leads to more natural, balanced results.

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What is Profhilo and how does it work?

Profhilo is an injectable treatment made from high-concentration hyaluronic acid.

Unlike traditional fillers, it isn’t designed to sit in one place or create shape. Instead, it spreads beneath the skin and works more like a bio-remodelling treatment.

Its main effects are:

  • Deep skin hydration

  • Improved elasticity

  • Smoother texture

  • Subtle firmness

  • Healthier overall glow

It stimulates collagen and elastin production while attracting water into the skin.

Think of Profhilo as improving the quality of the canvas, rather than changing the structure of the face.

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What are dermal fillers designed to do?

Dermal fillers also use hyaluronic acid, but they behave very differently.

They are thicker gels that stay where they’re placed and are carefully injected to:

  • Restore lost volume

  • Contour cheeks or jawline

  • Define lips

  • Support folds and lines

  • Improve facial proportions

In simple terms, fillers replace structure that time has reduced.

They are sculptural, precise and shape-focused.

Is Profhilo a filler?

This is one of the most common questions.

Short answer: no.

Although both contain hyaluronic acid, Profhilo is not classed as a dermal filler because:

  • it doesn’t create volume

  • it doesn’t change facial contours

  • it spreads rather than stays localised

So when patients search “Profhilo vs dermal fillers”, they’re really comparing two completely different treatment goals.

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Profhilo vs dermal fillers

FeatureProfhiloDermal Fillers

Main purpose

Skin hydration & quality

Structure & volume

Texture

Very fluid

Thicker gel

Placement

Spreads under skin

Stays where injected

Result

Glow, firmness, elasticity

Contour, lift, definition

Best for

Crepey, dull, ageing skin

Volume loss or shaping

Changes face shape?

No

Yes

Key differences at a glance

When Profhilo is the better choice

Profhilo is often ideal if you’re noticing:

  • Dull or dehydrated skin

  • Fine lines and crepey texture

  • Loss of elasticity

  • Early or mild ageing changes

  • “Tired” looking skin without obvious sagging

It’s particularly popular for patients who want subtle, natural improvement without altering their features.

Many people describe it as looking like a fresher version of themselves, rather than looking “treated”.

When dermal fillers are more appropriate

Fillers may be more suitable if you have:

  • Hollow cheeks or temples

  • Loss of mid-face support

  • Deep folds around the mouth

  • Thinning lips

  • A desire for more definition or contour

If structure has been lost, hydration alone won’t replace it. This is where fillers provide the support that the face needs.

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Which treatment is better for ageing skin vs volume loss?

A simple way to think about it:

Skin looking thin, dry or crepey → Profhilo

Face looking hollow or sagging → fillers

Both concerns → combination treatment

Ageing affects multiple layers of the face, so addressing only one layer rarely gives the most balanced result.

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Can Profhilo and fillers be combined safely and effectively?

Yes – and this is often where the best results happen.

Because they do different jobs, they can work together.

A common approach is:

  • Profhilo → improve skin quality
  • Fillers → restore shape and support

This combination can create results that look softer and more natural than using fillers alone, because the skin itself looks healthier.

At the L’Atelier clinic on Harley Street, treatment plans are typically layered and personalised rather than relying on a single product.

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In summary: Choosing the right approach starts with assessment

There isn’t a universal “better” option when it comes to injectable skin treatments.

It’s not really Profhilo vs dermal fillers.

It’s about understanding what your skin needs, what has changed structurally and what outcome you want to see.

A thorough medical consultation at our clinic in Harley Street allows your practitioner to assess these layers and recommend the right mix of hydration, support, or both.

The goal is always the same: natural, healthy-looking results that still feel like you.

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Profhilo vs Dermal Fillers: FAQs

Is Profhilo better than fillers?

Not better — just different. Profhilo improves skin quality, while fillers restore structure and volume.

How long does Profhilo last?

Typically around 6 months after the initial two-treatment course.

How long do dermal fillers last?

Depending on the area and product, usually 6–18 months.

Does Profhilo add volume to cheeks or lips?

No. It hydrates and firms but doesn’t sculpt or enhance.

Can I have both treatments at the same appointment?

Often yes, though your practitioner may stage treatments depending on your goals.

Which looks more natural?

Both can look very natural when performed conservatively and tailored to your anatomy.

Is there downtime?

Most patients experience mild swelling or small injection marks for 24–48 hours.

How do I know which one I need?

A personalised consultation is the safest and most accurate way to decide.

We always value your feedback. You can read all our patient reviews on our Google Profile

Your feedback is always important to us, as it helps us to improve our systems and processes in our continual pursuit of excellence. If you have any suggestions, comments, or concerns please get in touch.

I visited Duncan for polynucleotides and Botox two weeks ago and am delighted with the results. I was sceptical of the polynucleotides as it was my first time. I’m so glad I took the plunge, and it’s significantly changed the texture and darkness of the skin under my eyes. I’m excited to have the follow-up appointment!
Lane Allan
Lane Allan
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I had an incredible experience at L’Atelier! This was my first microneedling session and everyone was so kind, welcoming, and reassuring. Emma made me feel completely comfortable and did an amazing job the clinic is also incredibly clean and hygienic. I’m already seeing beautiful results within just 36 hours. Can’t wait for my next session!
Exceptional treatment. Reception were friendly and helpful. Duncan was, as before, approachable, straightforward, knowledgeable and filled me with confidence. The result was an improvement without being at all obvious. I will use L’Atelier Aesthetics again.
 Susie MacLean
Susie MacLean
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Loved my skin peel with Kate today. Kate is always so warm, welcoming and super informative about each step of the treatment. as well as the after care. I’m new to L’Atelier Aesthetics and can’t say enough great things about everyone. Looking forward to more treatments and a great skin journey!
Michelle Staphylas
Michelle Staphylas
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What about Profhilo Structura?

Profhilo Structura is a newer evolution within the Profhilo range, developed specifically to address age related changes in the deeper layers of the face, particularly the subcutaneous fat.

As we age, volume loss is not only related to the skin itself, but also to shifts and reduction in facial fat compartments, which can lead to flattening of the cheeks, loss of contour, and reduced structural support.

Profhilo Structura is designed to restore and support adipose tissue using a high concentration of stabilised hybrid hyaluronic acid complexes produced with NAHYCO technology.

Rather than acting as a traditional volumising filler, it works by improving deep firmness and tissue quality, creating a subtle lipolifting effect that helps re support the mid face while maintaining natural facial movement and expression.

This makes Profhilo Structura particularly suitable for patients experiencing early structural ageing who want support and firmness without obvious volume replacement.

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L’Atelier Aesthetics is based at the heart of Harley Street, London’s renowned medical district.

We serve central London and patients from around the UK and abroad. Find us on 101 Harley street by clicking the ‘Get Directions’ button below.

Opening hours
Monday
9:00 - 17:00
Tuesday
9:00 - 19:00
Wednesday
9:00 - 19:00
Thursday
9:00 - 19:00
Friday
9:00 - 17:00
Saturday
10:00 - 15:00
Sunday
Closed
L'Atelier Aesthetics
101 Harley St, London W1G 6AH
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Chemical peels; what are they and how do they work? 

Find out more here: https://www.latelieraesthetics.co.uk/treatments/skin/chemical-peels/

#chemicalpeel #skinexfoliation #skintransformation #chemicalpeelharleystreetNovember roundup:

1. First snow of the year on Harley Street
2. Launched our new IgniteRF machine
3. Welcomed our new marketing team (101 bevvy initiation included)
4. Filmed some lovely new website content
5. Duncan & Emma continued their cosy-pub tour of London
6. They’d also like everyone to know that Duke has a swish new bed and is thriving.
7. Emma insisted we mention her “best mushy peas ever” but conveniently left out the recipe… comment a 🫛 if you want it.
8. Birthday celebrations for one of our cuties
9. Sarah surprised us by popping back to London just in time for the Christmas chaos.
10. We sent her back to Abu Dhabi with fresh pink cheeks.
11. Kate watched her friend play for the All Blacks XV in Bath.
12. And then embraced full introspective mode sea-pondering in Malta.
13. She watched more rugby: All Blacks vs Wales in Wales
14. Bronte picked up a Muay Thai injury and hobbled around heroically for a week.
15. But made up for it with a Paris trip and the world’s nicest hot chocolate.
16. Plus a touch of retail therapy post-ZO training.
17. We had our team Christmas party, which delivered as always.
18. Secret Santa was a standout.
19. We ended the night at the cabaret

Bring on the rest of the festivities. 🎄✨JULÄINE (PLLA) is one of our go-to options when someone wants better skin integrity rather than added volume.

It sits in a slightly different category to fillers and biostimulators you may already know, working gradually to improve how the skin holds itself over time.

We use it where the skin is starting to look a little less supported (under-eyes, mid-face, jawline, neck) or when texture changes are becoming more noticeable.

The treatment is done as a short course over several weeks, with improvements developing naturally in the months that follow.

If you’re curious whether JULÄINE suits your skin goals, you can book a consultation with Dr Duncan for a personalised assessment.

#LAtelierSkin #SkinClinic #SkinExpert #AestheticMedicine
#CollagenSupport #PLLA #SkinRejuvenation #DermalHealth
#AestheticDoctor #HarleyStreetClinic #SkinQuality #JULAINE
★ ★ ★ ★ ★ 5.0 stars based on 254 Reviews
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